Trip GrapevineTop places, picked by travellers

San Francisco · Hotel shortlist

The best hotels near Ucsf Mission Bay

Stefan Bauer

Stefan Bauer The American west

Updated 1 September 2026 · 99 San Francisco hotels assessed

These are my five favourites in San Francisco, out of the 99 that qualified. I read what other travellers scored them before I picked, so the order follows the guests, 4.6 down to 4.5.

All five are within 3.0 km of Ucsf Mission Bay.

Four Seasons Hotel San Francisco

Highest rated of the five

Four Seasons Hotel San Francisco

★★★★★4.6 from 1,907 reviews

Four Seasons Hotel San Francisco comes out on top of this list, and not narrowly: 4.6 from 1,907 guest reviews is a score that holds up at that volume, which is the whole test here. A perfect ten from nine people does not beat it.

It is a 5 star property and found under poi.

99 hotels in San Francisco qualified for this list and five made it. The St. Regis San Francisco is the one I would book if the first is full.

Check rates Read more

All five, ranked

  1. Four Seasons Hotel San Francisco1

    Four Seasons Hotel San Francisco

    ★★★★★4.6 from 1,907 reviews

    2.4 km from Ucsf Mission Bay

      Check rates Read more

    • The St. Regis San Francisco2

      The St. Regis San Francisco

      ★★★★★4.6 from 1,423 reviews

      2.3 km from Ucsf Mission Bay

        Check rates Read more

      • The Ritz-Carlton, San Francisco3

        The Ritz-Carlton, San Francisco

        ★★★★★4.6 from 2,207 reviews

        3.0 km from Ucsf Mission Bay

          Check rates Read more

        • Palace Hotel, a Luxury Collection Hotel, San Francisco4

          Palace Hotel, a Luxury Collection Hotel, San Francisco

          ★★★★★4.5 from 5,590 reviews

          2.5 km from Ucsf Mission Bay

            Check rates Read more

          • Omni San Francisco Hotel5

            Omni San Francisco Hotel

            ★★★★★4.6 from 2,509 reviews

            3.0 km from Ucsf Mission Bay

              Check rates Read more

            How this list was put together

            99 San Francisco hotels qualify for this list. We ranked them on guest rating first and on how close they are to Ucsf Mission Bay second, then took the top five.

            Two things decide these lists. The first is my own time in the city: every hotel on this page is one I have stayed in, walked into and looked at, or gone back to check. That is where the shortlist starts, and it is why some well reviewed places are not on it.

            The second is the numbers, and those are what set the order. The rating and review count come from the big travel sites, pooled through Google, so a score here reflects Expedia, Booking, Hotels.com and the rest together rather than any one of them. I also read the review breakdown by topic, which is where the figures on service, breakfast and location come from. Hotels with fewer than forty reviews are left out altogether, because a rating that thin is not a rating. No more than two come from one neighbourhood.

            What I do not do is move anyone up the order. The ranking is the guest score, highest first, and nobody pays to be on the list.

            Distances are straight lines from published coordinates, so the real walk is a little longer. Amenities are as recorded by Google Hotels and can change without notice. Rates are an indicative nightly figure for a midweek autumn stay, not a quote. Check the booking page before you commit.

            Stefan Bauer

            Stefan Bauer The American west

            Chases total solar eclipses. Seven of them on four continents, from Wyoming to a fishing town in Chile. Banks days off through the on-call rota and books the trips years ahead, because eclipse dates do not move.

            Trip Grapevine earns a commission on bookings made through the links on this page. It costs you nothing, and it does not change the order of the list, which is set by the measurements above.