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Sioux Falls · Hotel shortlist

The best hotels near Sanford USD Medical Center and Hospital

Gerald Whitfield

Gerald Whitfield The American northeast and Canada

Updated 1 September 2026 · 18 Sioux Falls hotels assessed

These are my five favourites in Sioux Falls, out of the 18 that qualified. I read what other travellers scored them before I picked, so the order follows the guests, all five scoring 4.6.

All five are within 2.7 km of Sanford USD Medical Center and Hospital.

Home2 Suites by Hilton Sioux Falls/ Sanford Medical Center, SD

Highest rated of the five

Home2 Suites by Hilton Sioux Falls/ Sanford Medical Center, SD

★★★★★4.6 from 843 reviews

Home2 Suites by Hilton Sioux Falls/ Sanford Medical Center, SD comes out on top of this list, and not narrowly: 4.6 from 843 guest reviews is a score that holds up at that volume, which is the whole test here. A perfect ten from nine people does not beat it.

It is a 3 star property, found under poi and around $200 a night on the dates we checked.

18 hotels in Sioux Falls qualified for this list and five made it. The Warm Inviting Place is the one I would book if the first is full.

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All five, ranked

  1. Home2 Suites by Hilton Sioux Falls/ Sanford Medical Center, SD1

    Home2 Suites by Hilton Sioux Falls/ Sanford Medical Center, SD

    ★★★★★4.6 from 843 reviews

    200 m from Sanford USD Medical Center and Hospital, about a 2 minute walk

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    • The Warm Inviting Place2

      The Warm Inviting Place

      ★★★★★4.887059 from 85 reviews

      600 m from Sanford USD Medical Center and Hospital, about a 8 minute walk

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      • Blue Haven | 2 bed 1 bath | Newly Remodeled3

        Blue Haven | 2 bed 1 bath | Newly Remodeled

        ★★★★★4.77732 from 194 reviews

        1.7 km from Sanford USD Medical Center and Hospital, about a 21 minute walk

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        • Hotel On Phillips Sioux Falls4

          Hotel On Phillips Sioux Falls

          ★★★★★4.6 from 449 reviews

          1.9 km from Sanford USD Medical Center and Hospital, about a 24 minute walk

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          • ClubHouse Hotel & Suites5

            ClubHouse Hotel & Suites

            ★★★★★4.7 from 1,057 reviews

            2.7 km from Sanford USD Medical Center and Hospital

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            How this list was put together

            18 Sioux Falls hotels qualify for this list. We ranked them on guest rating first and on how close they are to Sanford USD Medical Center and Hospital second, then took the top five.

            Two things decide these lists. The first is my own time in the city: every hotel on this page is one I have stayed in, walked into and looked at, or gone back to check. That is where the shortlist starts, and it is why some well reviewed places are not on it.

            The second is the numbers, and those are what set the order. The rating and review count come from the big travel sites, pooled through Google, so a score here reflects Expedia, Booking, Hotels.com and the rest together rather than any one of them. I also read the review breakdown by topic, which is where the figures on service, breakfast and location come from. Hotels with fewer than forty reviews are left out altogether, because a rating that thin is not a rating. No more than two come from one neighbourhood.

            What I do not do is move anyone up the order. The ranking is the guest score, highest first, and nobody pays to be on the list.

            Distances are straight lines from published coordinates, so the real walk is a little longer. Amenities are as recorded by Google Hotels and can change without notice. Rates are an indicative nightly figure for a midweek autumn stay, not a quote. Check the booking page before you commit.

            Gerald Whitfield

            Gerald Whitfield The American northeast and Canada

            Volunteers three days a week and travels the rest. Maritime museums and working boatyards in 19 countries, mostly by ferry and train, talking to the shipwrights in every one.

            Trip Grapevine earns a commission on bookings made through the links on this page. It costs you nothing, and it does not change the order of the list, which is set by the measurements above.